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KMID : 0882420090770040517
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Korean Journal of Medicine
2009 Volume.77 No. 4 p.517 ~ p.521
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Cerebral sinovenous thrombosis associated with nephrotic syndrome
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Kim Hyun-Jung
Jung Duk-Eun
Byun Seung-Jae
Lee Yu-Min
Lee Ji-Eun
Ahn Seon-Ho
Song Ju-Hung
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Abstract
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Nephrotic syndrome is associated with proteinuria, hypoalbuminemia, edema, hyperlipidemia, and thromboembolic complications. Thromboembolic complications of nephrotic syndrome are common, especially in the renal vein, while cerebral venous thrombosis is a less frequent complication of minimal change nephrotic syndrome. The pathophysiology remains unclear, but various changes in coagulant and anticoagulant factors may be responsible. We report a case of cerebral venous thrombosis associated with nephrotic syndrome. A 19-year-old man was admitted with a headache and nausea. Cerebral thrombosis was diagnosed on brain computed tomography and magnetic resonance imaging. He recovered gradually after treatment with anticoagulants and achieved control of the nephrotic syndrome. A discussion of this case, coupled with a review of the literature, emphasizes that an early diagnosis is essential for anticoagulation therapy and a successful outcome.
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KEYWORD
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Cerebral thrombosis, Nephrotic syndrome
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